Limb Preservation With Isolated Limb Infusion for Locally Advanced Nonmelanoma Cutaneous and Soft-Tissue Malignant Neoplasms
نویسندگان
چکیده
منابع مشابه
Isolated Limb Infusion as a Limb Salvage Strategy for Locally Advanced Extremity Sarcoma.
BACKGROUND Treatment-resistant, locally advanced soft tissue sarcomas often require amputation for complete tumor extirpation. Isolated limb infusion (ILI) selectively delivers high-dose chemotherapy to the extremity in an attempt to achieve limb salvage. The aim of this study was to report perioperative and oncologic outcomes after ILI in patients with extremity soft tissue sarcomas. STUDY D...
متن کاملLimb preservation in patients with bone and soft tissue tumors.
Dr Siegel is from the Section of Orthopedic Oncology, University of Alabama at Birmingham, Orthopedics Specialties, Birmingham, Alabama. Dr Siegel has no relevant fi nancial relationships to disclose. Correspondence should be addressed to: Herrick J. Siegel, MD, Orthopedic Oncology, UAB Orthopedics Specialties Bldg, 1313 13th St S, Birmingham, AL, 35205 ([email protected]). doi: 10.3...
متن کاملTreatment of Locally Advanced Melanoma by Isolated Limb Infusion with Cytotoxic Drugs
Since its introduction in the late 1950s, isolated limb perfusion (ILP) has been the preferred treatment option for locally advanced melanoma and sarcoma confined to a limb. This treatment results in high response rates with a satisfying duration of response in both tumor types. A drawback of ILP, however, is the invasive and complex character of the procedure. Isolated limb infusion (ILI) has ...
متن کامل18F-fluorodeoxythymidine PET for evaluating the response to hyperthermic isolated limb perfusion for locally advanced soft-tissue sarcomas.
UNLABELLED Locally advanced soft-tissue sarcomas of an extremity can be treated either by amputation of the limb or by hyperthermic isolated limb perfusion (HILP) followed by resection of the tumor. In this study, the response to HILP was measured by PET with (18)F-fluorodeoxythymidine ((18)F-FLT). METHODS Ten patients with primary nonresectable soft-tissue sarcomas of an extremity underwent ...
متن کاملDoxorubicin in isolation limb perfusion in the treatment of advanced limb soft tissue sarcoma.
Hyperthermic antiblastic perfusion/HAP) has been proven to be an effective neoadjuvant treatment in the treatment of advanced soft tissue limb sarcoma. As a matter of fact high percentage of limb sparing surgery, local control and functional results have been obtained wide this technique. Many antineoplastic drugs have been associated to hyperthermia by isolation limb perfusion, the aim of this...
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ژورنال
عنوان ژورنال: Archives of Surgery
سال: 2011
ISSN: 0004-0010
DOI: 10.1001/archsurg.2011.139